Trombólisis

Francisco Eduardo González Acosta, Oscar Alberto Sáenz, Paola Bonilla, Jorge Russi, Angélica Rojas, Diana Hurtado

Resumen


En la homeostasis de un individuo sano se desarrollan coágulos para prevenir la pérdida de sangre, pero las fallas del equilibrio hemostático pueden ocasionar obstrucción aguda de una arteria como fenómeno fisio­patológico principal, que puede beneficiarse del tratamiento trombolítico que consiste en la administración, por vía endovenosa o en ocasiones intraarterial, de medicamentos capaces de destruir los coágulos de fibrina y permitir que se restaure el flujo sanguíneo en el vaso sanguíneo. Esto se hace para evitar complicaciones como infarto cerebral, embolia pulmonar, trombosis venosa profunda e infarto agudo del miocardio.

El siguiente documento es una revisión bibliográfica de la terapia fibrino­litica y su uso en estas entidades, teniendo en cuenta las recomendaciones de la Agency for Healthcare Research and Quality (AHRQ), usando PubMed como base datos de búsqueda principal. Se obtuvieron artículos sobre trombólisis en infarto agudo del miocardio, trombembolismo pulmonar y accidente cerebrovascular y según la pertinencia se procedió a su análisis para generar una recomendación.


Palabras clave


Terapia Trombolítica; Infarto agudo de miocardio; Accidente cerebrovascular; Tromboembolismo pulmonar

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DOI: http://dx.doi.org/10.18270/rsb.v8i1.2379

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